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Open your operating system's command shell and type the following lines in bold.
C:\>cd C:\Program Files\Mozilla Firefox
C:\Program Files\Mozilla Firefox>set MOZ_NO_REMOTE=1
C:\Program Files\Mozilla Firefox>firefox.exe -p
C:\Program Files\Mozilla Firefox>firefox.exe -Profile "C:\Path\to\profile"
Linux & OSX:
$ cd /firefox/location
$ export MOZ_NO_REMOTE=1
$ ./firefox -p
$ ./firefox -Profile "/path/to/profile"
To simplify the process, you can create either a batch file or shell script to quickly open multiple instances of Firefox at once. Just remember that each instance must not share its profile with any of the other active instances. Removing the profile lock file while Firefox is running is not recommended.
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