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This project will run for at least 3 years. Financing is in place.
Every quarter we will be taking best "docking" results, testing the candidates in cell and animal models of disease and developing through medicinal chemistry the best candidates as potential drugs.
We will then file new drug applications (INDs) with the FDA to test in human clinical trials. The TS Alliance will help in recruiting doctors and patients for the clinical trials.
We are making real drugs to fight TSC. TSC is [a] Rosetta stone for cancer.
We are doing this right.
We will add new targets, add new drug candidate libraries, and improve docking-based virtual library screening. We plan on being the world leader in computational design of drugs, and will offer $1,000,000 prize later in year for improvements in computational methods that improve our ability to enrich for real potential drug leads from the candidate libraries.
As far as financial backing, we have what it takes to get the job done, and will not stop until this problem is solved.