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There are a great abundance of Gnutella P2P programs for Linux. Popular clients include LimeWire, Gtk-Gnutella, Napshare, and Qtella. A quick search on FreshMeat will find them all.
There are several IRC clients for Linux. Among the best are X-Chat and BitchX. See the IRC FAQ for more information regarding downloading files from IRC networks
Some time ago there was a KaZaA text-based client for Linux. This project (maintained by the people at KaZaA has been killed). If you're using a *nix, you're probably beyond using KaZaA anyway.
There is an official eDonkey client for Linux, see eDonkey's Website for details and installation instructions.
Several other clients for eDonkey on *nix exist, but none that I've tried work as well as the official one.
Direct Connect on Linux sucks. This client and this client are the two best I've used.
Pan is by far the best I've used.
Note: Problems with compiling / installing *nix software should be taken to the Unix Forum