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Cisco routers use a CLI (Command Line Interface)instead of a GUI interface. You should be familiar with changing and saving paramenters using the Cisco CLI before proceding. The command for changing MMS is ip tcp adjust-mss mss value.
To set the MTU to 1400 bytes use the following command example:
Additional Notes: If you are experiencing problems related to MTU you should also adjust the MTU on all PCs and Servers connected to the network.
How do I use DrTCP to change the MTU on my NIC?.