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| | | | FAQ Revisions | Editors: KeysCapt  , lilhurricane , slash , Dersgniw
Last modified on 2007-05-11 17:12:24
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2.5 UD Projects·What projects can I crunch?
·(Archived) What is LigandFit?
·How does the Web Performance Testing work?
·(Archived) What is Rosetta & the Human Proteome Folding Project?
·(Archived) What is PatriotGrid?
·(Archived) How about ANTHRAX processing?
·(Archived) What about smallpox?
·(Archived) What is THINK?
| | | The current project is Cancer. You can pick whichever project(s) you like by going to your Profile page on the grid.org site. Select the profile you wish and check the appropriate boxes.
Select the project(s) you wish to crunch
The projects may change over time and this faq will be updated to indicate any changes.
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by slash edited by lilhurricane
last modified: 2006-09-09 09:44:13 | | | LigandFit is the second phase of the United Devices cancer research project. LigandFit replaces Think and is designed to further refine the results from the Think phase to find more information about the molecules from the Think phase.
The UD Agent essentially is the same and for the user only minor changes can be noticed.
More info on the UD Boards about Ligandfit.
This project ended 4/27/07 and Grid has closed officially
Thanks to all for their contributions..and especially..their dedication
See:
»[UD] All Good Things Come To An End...
»(Archived) Team Discovery Roster and Statistics 4/26/2007
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by slash edited by lilhurricane
last modified: 2007-04-26 23:05:42 | | | This project, also known as Exodus, will work in the background of select computers and will test web performance. Performance testing basically simulates a quick Web browser session to a given Web site and measures what happens. There are two types of performance testing that UD will host: "Load Testing", which measures a site's ability to handle a peak in traffic time by simulating a series of increased hits, and "Monitoring," a periodic testing that provides continual performance checks over time. To see an overview of the project go here.
A recent update from UD's Member News forum:
July 18, 2001
Web Performance Testing Project Begins On UD Network
UD has begun running the previously announced Web Performance Testing Project across select PCs on the UD Member network. If your PC is opted in to run all UD projects, it may be selected to participate in a Web Performance Test sometime in the future. Given the nature of Web Performance Testing, not all PCs that are eligible to participate will be called upon for this project. For those PCs that do receive a Web Performance Testing Project, this application will work as a secondary task, in the background, while the Cancer Research project continues to run. PCs participating in Web Performance Tests earn points for the Make-A-Wish Foundation donations and earn extra points for individuals. All members can opt out or opt in to the Web Performance Test Project by visiting their "device profile" page. If your PC is set to run the Cancer Research Project only, then it will not run a Web Performance Test unless you modify your device profile to allow it to do so.
To find out more about the Web Performance Testing Project please check out our information site.
Also please see the known issues board regarding the Web Performance Test CPU Time 'Freezes bug.
--------------------
Chris Sherman
Senior Director, UD Member Services
--
Thanks to RClarkofNC for the post on this info.
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by Equinox6 edited by KeysCapt | | | Rosetta is a new project application launched on November 16th, 2004.
One of the greatest challenges facing scientists is to find functions for all of the proteins that are encoded in the Human Genome. When human protein structures are known, scientists can use them to research disease treatments and cures.
Rosetta is fairly memory intensive. The required memory for Rosetta to run is 256 MB ram. If your computer does not have this much ram you will be given cancer work units to crunch.
To have an immediate scientific impact, completing an entire prediction run for the human genome would ideally take less than a year. Before the existence of Grid.org this project wasn't thought possible -- now, the project is on its way to being completed.
Note: This project has ended
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by lilhurricane
last modified: 2006-09-09 09:42:58 | | | The PatriotGrid is a general term being used by grid.org to characterize any of their distributed computing projects that fight bio-terrorism.
The only current PatriotGrid project is the Smallpox Grid which is for drug candidates to cure smallpox (after infection).
PatriotGrid is optional and can either be run in conjunction with the cancer project or by itself.
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by slash edited by lilhurricane
last modified: 2006-02-06 17:15:15 | | | UD Anthrax Project
The Anthrax Program has finished. The information below is out-dated, but left here for informational value. (kc)
UD have now started another project, to fight against the threat of Anthrax.
If you do not wish to participate in this new project, and to run only the Cancer project, you can update your profile at »https://members.ud.com/services/home.htm and click "My Device Manager" and then "Profiles".
Note - this is a new Primary Project having the same priority on your computer as the Cancer project, unlike the web performance testing which is a secondary project.
This also explains why we have the new .NET graphic on the Application windows of the UD agent as this new project is being sponsored by Microsoft.
The Anthrax Research Project will take advantage of and build upon the success of the Intel-United Devices Cancer Research Project. Like that project, the Anthrax Research Project relies on volunteered computers to screen billions of drug-like molecules. The individual "virtual" molecules are screened for binding capacity on a protein known to have a role in anthrax's toxicity to humans.
Also like the cancer research, this is a public good project United Devices will not sell, retain rights to, or profit from the project results. Whatever results are uncovered will be made available to the United States government and other friendly governments, who can use them to further develop a drug therapy in a lab. The goal is to develop a drug that can be used in the advanced stages of the disease currently anthrax can only be treated with antibiotics in its earliest stages.
Once completed, United Devices will return its focus to the cancer project. As per United Devices Member Policy, Members who want to commit their computing cycles exclusively to cancer research can do so.
More Information from United Devices:
THE ANTHRAX PROJECT: How It Affects the Cancer Project
Since the Anthrax project runs on the same THINK software, and is based on the same virtual screening principals as the Cancer Research Project, details on that project can be reviewed for more specific answers and information about the anthrax screening.
Please note that United Devices remains committed to the Cancer Research Project. Our partners in Cancer Research Oxford, NFCR and Intel were all included in our decision to take on this task, and are all deeply supportive and instrumental in offering this new project to UD Members. These partners and United Devices would like to encourage our Members to tackle this new research.
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by KeysCapt edited by lilhurricane
last modified: 2006-02-06 17:15:29 | | | Grid.org (United Devices) started on Feb. 5, 2003 the Smallpox Grid project in collaboration with the US Department of Defense, Accelrys, and IBM. The goal of this project is to find a post-infection cure for smallpox. A vaccine already exists, but it is more risky than some people would like it to be.
All of the results from the project will be sent to the United States Department of Defense’s Office of the Secretary of Defense. This project can be opted out of by going to your Member Homepage and then to the device profiles section. Detailed instructions can be found here.
Information from grid.org: The project employs computational chemistry to analyze chemical interactions between a library of 35 million potential drug molecules and several protein targets on the smallpox virus in the search for an effective anti-viral drug to treat smallpox post-infection.
Individuals can participate in the Smallpox Research Grid Project by downloading a screensaver [The UD Agent which can also be run in the tray as well] at grid.org. The screensaver [or UD Agent] will unobtrusively donate the computer’s idle processing power and link it into a worldwide Grid that will act as a virtual supercomputer capable of analyzing billions of molecules in a fraction of the time it would take in a laboratory. Once processing is complete, the program will send results back to United Devices’ data center, powered by an IBM infrastructure, and will request new data to analyze. The new data will then be analyzed by the individual machine and the results returned the next time the computer user connects to the Internet
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by slash edited by lilhurricane
last modified: 2005-09-12 23:07:30 | | | THINK was the original UD client application, and it has finished, to be replaced by Ligandfit.
THINK was a drug discovery software program. The program appraises each of hundreds of millions of molecules to see if they are likely to interact with a target protein. THINK calculates and studies the many possible shapes, or conformers, the molecule might adopt interacting with the protein. This process is called virtual screening of the molecules.
THINK explores the 3-dimensional shapes each molecule might adopt. Each new shape of the molecules may help the right parts of the molecule interact with the protein target. THINK does this very fast-so fast your monitor can't show every molecule or conformation. This is why the conformation number is moving so rapidly. The total number of conformations differs molecule to molecule. Some molecules may have more bonds or flexibility, and thus will have more conformers.
The Current Protein Target represents a protein that the molecules may interact with. The protein has already been determined to be a possible target for cancer therapy. It is one of only a few protein targets that the millions of molecules are screened against for this project, so the same protein target will be featured on the screen saver for a while.
When a molecular conformation docks successfully and triggers an interaction with the protein, it registers as a "hit." Hits have different levels of strength, but any one hit may be the one that will ultimately lead to a cure. All hits are recorded, ranked for strength of interaction, and filed for the next stage of the project.
More information on computational chemistry can be found at the Oxford University site.
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by Equinox6 edited by lilhurricane
last modified: 2005-09-23 19:39:04 |
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