said by Camelot One:Anything done in software can be easily undone, possibly without you knowing. A hard solution is better. Depending on how paranoid you are depends on how far you go. For me the tape would be more than enough. I don't understand why they don't have both a slide shutter and an LED to let you know when they are in use. You'd think after the said by neonhomer:
Black tape is the easiest, and effective.
If you are trying to disable it to prevent prying eyes, keep in mind that black tape over the camera would still allow audio to be recorded/transmitted.
Disabling in device manager is the best option.