The 49ers looked anything, but invincible, last Sunday at Minnesota. Say anything you want about traveling to the West Coast and early start times they were thrashed soundly by a team that lost a week ago to bottom feeding Indy.
A great match up would be Seattle vs the 49ers. Seattle looked awesome against the Packers. Never mind the end controversy the Packers deserved to lose.
I'll take the Packers over the Saints. Two teams with suspect defenses.