Video drivers? Since you mentioned nVidia, I am guessing that is what you are asking about.
I am running a leading edge Linux (Siduction Linux) with an ATI HD6770 card and I use the open source radeon driver. It works just fine except for operating temperature, which is too hot with the standard power settings. I have learned to set my power profile from default to low and my temperatures stay reasonable. I am not a gamer, either.
Trying to use the closed source fglrx driver is an on and off proposition. It usually does not work, but then there will be a magical combination of technology stack where it does work for a while. Then, either a kernel upgrade or an Xorg upgrade will make things incompatible, again. So, I just stay with the open source driver.
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