If by personal information you mean files on your computer you could set up Sandboxie to do this. I use Sandboxie to isolate my internet facing programs from the rest of my computer. When I open my browser it is "sandboxed" and anything I open with it such as a pdf would open and sandbox my pdf reader.
I can also set restrictions as to what can open and have internet access in the sandbox. It's also possible to restrict access to files, folders or partitions by anything running in that sandbox.
Sandboxie is often overlooked but I wouldn't surf without it. My other layers include an AV and 2 on-demand scanners. I also run a HIPS program to alert me in the off chance anything would run without my permission. Recent backups of data are also important. -- If we quit voting, will they all just go away?