said by neat Image :

Neat Image v6.0 32-bit /Win

* Neat Image now can build noise profile using smaller image areas;
this is useful when the input image contains only small featureless areas
* Increased profiling speed (Auto Profile and Auto Fine-Tune)
* Increased filtration speed (several speed optimizations in the noise filter)

* Improved Neat Image plug-in's controls used to adjust the startup behaviour, settings of the plug-in in Photoshop actions and in smart filters:

The Actions menu is now used to adjust the plug-in behaviour in an action being recorded or in a smart filter being configured.
Also, the same Actions menu is used to configure the default startup behaviour of the plug-in. The old method of using the Defaults in Options is now completely replaced with the Action menu in plug-in. Please see the user guide for more details.

+ Plug-in: added support for Adobe Photoshop CS4 (32-bit)
+ Plug-in: added support for Adobe Photoshop Elements 7.0
* Plug-in: improved installer compatibility with localized versions of Photoshop

* Plug-in: improved behavior of the plug-in in smart filters in Photoshop CS4 and CS3
* Plug-in: improved recording of noise profiles and presets in Photoshop actions
* Plug-in: modified error reporting for smoother Photoshop-based batching

* Improved metadata compatibility with Nikon D90, D300, D700, D3, D60, and several more new Nikon cameras
* Improved metadata compatibility with older Nikon DSLR cameras
* Improved metadata compatibility with Nikon D1X with new firmware

* An image sent to Neat Image standalone via "Send To", "Open With" or drag-n-drop to Neat Image icon will now open either in Filtration Queue or Filtration Job Editor depending on the "Auto create new job on startup" setting in Neat Image options

* Improved functionality of "Save Output As" for multiple output images being saved in Filtration Queue (both automatic and manual saving of individual images is now available)

* Cosmetic improvements in the Batch Profiler, Profile Converter, Profile Viewer

* Improved compatibility with some invalid TIFFs saved by Capture 1
* Improved support of some compressed TIFFs

* Improved compatibility with Windows Vista

- Several other bug fixes and corrections