Make sure your selecting the correct serial port and that its secured good. Also make sure your serial ports are enabled in your bios. Some manufacturers disable them to free up resources for faster boot times. Also a factory reset is usually a good idea. IF thats unhelpful try looking here 'http://www.cisco.com/en/US/products/sw/iosswrel/ps5013/prod_release_note09186a0080087143.html'